Domain

CD4, extracellular (IPR015274)

Short name: CD4-extracel

Domain relationships

None.

Description

This domain adopts an immunoglobulin-like beta-sandwich with seven strands in 2 beta sheets, in a Greek key topology. It is predominantly found in the extracellular portion of CD4 proteins, where it enables interaction with major histocompatibility complex class II antigens [PMID: 8493535].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam