X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain (IPR015251)

Short name: PepX_N_dom

Overlapping homologous superfamilies

Domain relationships



This N-terminal domain adopts a secondary structure consisting of a helical bundle of eight alpha helices and three beta strands, with the last alpha helix connecting to the first strand of the catalytic domain. The first strand of the N terminus also forms a small parallel beta sheet with strand five of the catalytic domain. This domain mediates dimerisation of the protein, with two proline residues present in the domain being critical for interaction [PMID: 12377124].

GO terms

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0008239 dipeptidyl-peptidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.