MPT63-like (IPR015250)

Short name: MPT63-like

Overlapping homologous superfamilies

Domain relationships



MPT63 is a secreted protein of unknown function that is specific to Mycobacterium tuberculosis. MPT63 assumes a beta-sandwich structure consisting of two antiparallel beta-sheets (similar to an immunoglobulin-like fold), and an additional small, antiparallel beta-sheet. The longer-stranded beta-sheet is made up of four antiparallel beta-strands. The shorter-stranded beta-sheet consists of five beta-strands, four of which form an antiparallel beta-sheet. The exact function of this domain is unknown, though a putative role includes involvement in host-bacterial interactions involved in endocytosis or phagocytosis, possibly during bacterial internalisation [PMID: 12441386].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005615 extracellular space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
  • PD886639 (Immunoprotect_excell_Ig-like)