Nuclear RNA export factor Tap, RNA-binding domain (IPR015245)

Short name: Tap_RNA-bd

Overlapping homologous superfamilies

Domain relationships



This domain adopts a structure consisting of an alpha+beta sandwich with an antiparallel beta-sheet, arranged in a 2(beta-alpha-beta) motif. It is mainly found in mRNA export factors, which mediate the sequence nonspecific nuclear export of cellular mRNAs as well as the sequence-specific export of retroviral mRNAs bearing the constitutive transport element [PMID: 11854490].

GO terms

Biological Process

GO:0006406 mRNA export from nucleus

Molecular Function

GO:0003723 RNA binding

Cellular Component

GO:0005737 cytoplasm
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.