Family

Phosphatidate cytidylyltransferase, mitochondrial (IPR015222)

Short name: Tam41

Family relationships

None.

Description

Tam41 is a mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) that catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. It is required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane [PMID: 19114592, PMID: 23623749].

GO terms

Biological Process

GO:0032049 cardiolipin biosynthetic process

Molecular Function

GO:0004605 phosphatidate cytidylyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
Pfam
PANTHER