Family

Ubiquitin-related modifier 1 (IPR015221)

Short name: Urm1

Family relationships

None.

Description

Ubiquitin related modifier 1 (Urm1) is a ubiquitin related protein that modifies proteins in the yeast ubiquitin-like urmylation pathway [PMID: 16864801]. Structural comparisons and phylogenetic analysis of the ubiquitin superfamily has indicated that Urm1 has the most conserved structural and sequence features of the common ancestor of the entire superfamily [PMID: 14551258]. Urm1 acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln) [PMID: 21209336].

GO terms

Biological Process

GO:0034227 tRNA thio-modification

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
HAMAP
PIRSF
Pfam
PANTHER