Domain

SANT associated (IPR015216)

Short name: SANTA

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

The SANTA domain (SANT associated) is approximately 90 amino acids in length and is conserved in eukaryotes. It is sometimes found in association with the SANT domain (IPR001005, also known as the Myb-like DNA-binding domain) implying a putative function in regulating chromatin remodelling. Sequence analysis has showed that the SANTA domain is likely to form four central beta-sheets with three flanking alpha-helices. Many conserved hydrophobic residues are present which implies a possible role in protein-protein interactions.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam