Domain

Lyase, N-terminal (IPR015176)

Short name: Lyase_N

Domain relationships

Description

This entry represents a domain predominantly found in chondroitin ABC lyase I, adopting a jelly-roll fold topology consisting of a two-layered bent beta-sheet sandwich with one short alpha-helix. The convex beta sheet is composed of five antiparallel strands, whilst the concave beta-sheet contains five antiparallel beta-strands with a loop between two consecutive strands folding back onto the concave surface. This domain is required for binding of the protein to long glycosaminoglycan chains [PMID: 12706721].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CATH-Gene3D
Pfam