Domain

Type III secretion system effector delivery regulator TyeA (IPR015144)

Short name: T3SS_TyeA

Domain relationships

Description

This domain is composed of two pairs of parallel alpha-helices, and interacts with the bacterial protein YopN via hydrophobic residues located on the helices. Association of TyeA with the C terminus of YopN is accompanied by conformational changes in both polypeptides that create order out of disorder: the resulting structure then serves as an impediment to type III secretion of YopN [PMID: 15701523].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
Pfam