Domain

Stannin cytoplasmic (IPR015137)

Short name: SNN_cytoplasm

Overlapping homologous superfamilies

Domain relationships

None.

Description

This domain forms a distorted cytoplasmic helix that is partially absorbed into the plane of the lipid bilayer with a tilt angle of approximately 80 degrees from the membrane normal. It interacts with the surface of the lipid bilayer, and contributes to the initiation of the apoptotic cascade on binding of the unstructured linker domain to dimethyltin [PMID: 16246365].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam