Domain

Tumour suppressor p53-binding protein-1 Tudor domain (IPR015125)

Short name: 53-BP1_Tudor

Domain relationships

None.

Description

This domain consist of two tandem tudor folds with a deep pocket at their interface. The domain is essential for the recruitment of proteins to double stranded breaks in DNA, which is mediated by interaction with methylated Lys 79 of histone H3 [PMID: 15525939].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam