Domain

Exotoxin A catalytic domain (IPR015099)

Short name: Exotox-A_cataly_dom

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

Prokaryotic exotoxin A catalyses the transfer of ADP ribose from nicotinamide adenine dinucleotide (NAD) to elongation factor-2 in eukaryotic cells, with subsequent inhibition of protein synthesis [PMID: 8692916].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
Pfam