Domain

Far upstream element-binding protein, C-terminal (IPR015096)

Short name: FUBP_C

Domain relationships

None.

Description

This entry represents a domain found in the C terminus of Far upstream element-binding protein 1/2 (FUBP1/2) [PMID: 8940189]. FUBP1 regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter [PMID: 8125259, PMID: 28076379]. FUBP2, also known as KSRP (K homology-type splicing regulatory protein), is an single-strand-RNA binding protein that integrate different levels of gene expression and is required for proper immune response, lipid metabolism, cell fate decisions, and tissue regeneration [PMID: 24845017].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003676 nucleic acid binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam