Domain

Nucleoporin, Nup133/Nup155-like, N-terminal (IPR014908)

Short name: Nucleoporin_Nup133/Nup155_N

Domain relationships

None.

Description

Nucleoporins are the main components of the nuclear pore complex (NPC) in eukaryotic cells, and mediate bidirectional nucleocytoplasmic transport, especially of mRNA and proteins. RNA undergoing nuclear export first encounters the basket of the nuclear pore and many nucleoporins are accessible on the basket side of the pore [PMID: 10191094, PMID: 11684705].

This entry represents the N-terminal domain of nucleoporin 133 (Nup133) and other nucleoporins, including Nup155, Nup15 and Nup170. It forms a seven-bladed beta propeller structure [PMID: 15557116].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam