Domain

Ku, C-terminal (IPR014893)

Short name: Ku_PK_bind

Domain relationships

None.

Description

The non-homologous end joining (NHEJ) pathway is one method by which double stranded breaks in chromosomal DNA are repaired. Ku is a component of a multi-protein complex that is involved in the NHEJ. Ku has affinity for DNA ends and recruits the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). This domain is found at the C-terminal of Ku which binds to DNA-PKcs [PMID: 14672664].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016817 hydrolase activity, acting on acid anhydrides

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
GENE3D
Pfam
SUPERFAMILY