Domain

Transcription factor DP, C-terminal (IPR014889)

Short name: Transc_factor_DP_C

Domain relationships

None.

Description

DP forms a heterodimer with E2F and regulates genes involved in cell cycle progression. The transcriptional activity of E2F is inhibited by the retinoblastoma protein which binds to the E2F-DP heterodimer [PMID: 16360038] and negatively regulates the G1-S transition.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
CDD
Pfam