Spore coat protein CotH (IPR014867)

Short name: Spore_coat_CotH

Overlapping homologous superfamilies


Family relationships



Members of this family include the Bacillus subtilis spore coat protein H (CotH). Assembly of CotH requires both CotE and GerE and is required for the correct assembly of both inner and outer layers of the coat. CotH appears to be a structural component of the coat being localised at the interface of the 2 coat layers [PMID: 17114257, PMID: 10198031, PMID: 14762006]. Furthermore, CotH has been shown to be an atypical protein kinase. CotH-dependent phosphorylation of CotB and CotG is required for the efficient germination of B. subtilis spores [PMID: 27185916].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.