Domain

Glycolipid transfer protein domain (IPR014830)

Short name: Glycolipid_transfer_prot_dom

Domain relationships

None.

Description

Glycolipid transfer protein (GLTP) is a cytosolic protein that catalyses the intermembrane transfer of glycolipids such as glycosphingolipids, glyceroglycolipids, and possibly glucosylceramides, but not of phospholipids. The GLTP protein consists of a single domain with a multi-helical structure consisting of two layers of orthogonally packed helices [PMID: 15504043, PMID: 16309699].

The GLTP domain is also found in trans-Golgi network proteins involved in Golgi-to-cell-surface membrane traffic [PMID: 15107860].

GO terms

Biological Process

GO:0120009 intermembrane lipid transfer

Molecular Function

GO:0120013 intermembrane lipid transfer activity

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY
Pfam