Domain

Argonaute, linker 1 domain (IPR014811)

Short name: ArgoL1

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

ArgoL1 is a region found in argonaute [PMID: 16216572] proteins. It normally co-occurs with BAG domain (IPR003103) and Piwi domain (IPR003165). It is a linker region between the N-terminal and the PAZ domains. It contains an alpha-helix packed against a three-stranded antiparallel beta-sheet with two long beta-strands (beta8 and beta9) of the sheet spanning one face of the adjacent N and PAZ domains. L1 together with linker 2, L2, PAZ and ArgoN forms a compact global fold [PMID: 16061186].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART