Domain

MutL, C-terminal, dimerisation (IPR014790)

Short name: MutL_C

Domain relationships

None.

Description

MutL and MutS are key components of the DNA repair machinery that corrects replication errors [PMID: 8811176]. MutS recognises mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signalling complex for repair. The N-terminal region of MutL contains the ATPase domain and the C-terminal is involved in dimerisation [PMID: 15470502].

GO terms

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART