Poly(A)-specific ribonuclease, RNA-binding (IPR014789)

Short name: PolyA-riboNase_RNA_binding

Overlapping homologous superfamilies

Domain relationships



This domain corresponds to the RNA binding domain of Poly(A)-specific ribonuclease (PARN). PARN is a 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails [PMID: 9736620].

GO terms

Biological Process

GO:0006402 mRNA catabolic process

Molecular Function

GO:0003723 RNA binding
GO:0046872 metal ion binding
GO:0004535 poly(A)-specific ribonuclease activity

Cellular Component

GO:0005737 cytoplasm
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.