Domain

Double-stranded RNA-binding domain (IPR014720)

Short name: dsRNA-bd_dom

Domain relationships

Description

The double-stranded RNA-binding domain (dsRBD), which is found in a variety of proteins, shares a common structure with the N-terminal domain of ribosomal protein S5, namely an alpha-beta(3)-alpha structure that folds into two layers, alpha/beta [PMID: 7628456]. The dsRBD is found in a variety of functionally distinct proteins, including Drosophila staufen proteins (five copies of motif), dsRNA-dependent protein kinase pkr, and RNase III.

This entry represents the dsRBD and other structurally related domains.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam
GENE3D
PROSITE profiles