Neuropilin (IPR014648)

Short name: Neuropilin

Family relationships


Neuropilins are essential multifunctional vertebrate cell surface receptors [PMID: 23116416]. They function as receptors for axon guidance factor semaphorin class 3 (Sema3), vascular endothelial growth factor (VEGF) and placenta growth factor-2 (PLGF-2).

GO terms

Biological Process

GO:0001525 angiogenesis
GO:0007411 axon guidance
GO:0038084 vascular endothelial growth factor signaling pathway

Molecular Function

GO:0017154 semaphorin receptor activity
GO:0005021 vascular endothelial growth factor-activated receptor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.