A-agglutinin-binding subunit Aga2 (IPR014404)

Short name: Aga2

Family relationships



Aga2 is an adhesion subunit of a-agglutinin of a-cells. Saccharomyces cerevisiae a and alpha cells express the complementary cell surface glycoproteins a-agglutinin and alpha-agglutinin, respectively, which interact with one another to promote cellular aggregation during fungal mating [PMID: 1756718]. Aga2 contains the adhesive domain, and its C-terminal 10 amino acids (sequence GSPINTQYVF) can act as a ligand for alpha-agglutinin [PMID: 11292808].

GO terms

Biological Process

GO:0000752 agglutination involved in conjugation with cellular fusion

Molecular Function

GO:0050839 cell adhesion molecule binding

Cellular Component

GO:0009277 fungal-type cell wall

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.