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Overview
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Pathways & interactions
Coagulation factor XII/hepatocyte growth factor activator (IPR014394)
Short name: Coagulation_fac_XII/HGFA
Overlapping homologous superfamilies
None.
Family relationships
- Peptidase S1A, chymotrypsin family (IPR001314)
- Coagulation factor XII/hepatocyte growth factor activator (IPR014394)
Description
This entry represents coagulation factor XII/hepatocyte growth factor activator (HGFA). Both proteins included in this entry show a homologous domain structure [PMID: 20402766]. The proteins contain a C-terminal serine peptidase domain that belongs to MEROPS peptidase family S1A (clan PA(S)) [PMID: 20558624, PMID: 19850327].
GO terms
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004252 serine-type endopeptidase activity
Cellular Component
GO:0005615 extracellular space
Contributing signatures
- PIRSF001146 (Factor_XII_HGFA)