Aldehyde oxidase (IPR014313)

Short name: Aldehyde_oxidase

Overlapping homologous superfamilies

Family relationships


Aldehyde oxidase catalyses the reaction: aldehyde + H2O + O2 = a carboxylic acid + H2O2

It contains molybdenum, [2Fe-2S] centres and FAD. It also oxidizes quinoline and pyridine derivatives. It is probably identical to retinal oxidase (EC: [PMID: 10190983].

Aldehyde oxidase oxidises various aliphatic and aromatic aldehydes using oxygen as an electron acceptor. It has a molecular mass of 132 kDa and consists of three non-identical subunits with molecular masses of 88, 39, and 18 kDa. It belongs to the xanthine oxidase family. This enzyme shows high thermostability [PMID: 14659539].

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0051287 NAD binding
GO:0046872 metal ion binding
GO:0016491 oxidoreductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.