S-formylglutathione hydrolase (IPR014186)

Short name: S-formylglutathione_hydrol

Overlapping homologous superfamilies

Family relationships


This entry describes proteins from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC: Eukaryotic members, particularly the human protein, are better known as esterase D (EC:, an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well.

GO terms

Biological Process

GO:0046294 formaldehyde catabolic process

Molecular Function

GO:0018738 S-formylglutathione hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.