Water stress and hypersensitive response domain (IPR013990)

Short name: WHy-dom

Overlapping homologous superfamilies


Domain relationships


Water Stress and Hypersensitive response (WHy) domain is a region of unknown function found in several plant proteins involved in either the response to water stress or the response to bacterial infection [PMID: 15598830]. It is also found in some bacterial and archaeal proteins whose functions are not currently known. This domain is approximately 100 amino acids long and is composed of alternating hydrophobic and hydrophilic residues, with an almost invariant NPN motif at the N terminus. The predicted secondary structure is a novel fold consisting mostly of beta strands and a C-terminal alpha helix.

GO terms

Biological Process

GO:0009269 response to desiccation

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.