Domain

Metal-dependent hydrolase HDOD (IPR013976)

Short name: HDOD

Domain relationships

None.

Description

This domain is found in a superfamily of enzymes with a predicted or known phosphohydrolase activity. These members appear to be involved in the nucleic acid metabolism and signal transduction or possibly other functions and are restricted to bacteria, primarily the proteobacteria. The fact that all the highly conserved residues in the HD superfamily are histidines or aspartates suggests that coordination of divalent cations is essential for the activity of these proteins [PMID: 9868367].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
GENE3D