Domain

Polyketide synthase, ketoreductase domain (IPR013968)

Short name: PKS_KR

Domain relationships

Description

This domain is found in polyketide and fatty acid synthases that catalyse the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group [PMID: 23790488].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam