Domain

Replication factor A, C-terminal (IPR013955)

Short name: Rep_factor-A_C

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

Replication factor A (RP-A) binds and subsequently stabilises single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. It also plays an essential role in several cellular processes in DNA metabolism including replication, recombination and repair of DNA [PMID: 10713540]. Replication factor-A protein is also known as Replication protein A 70 kDa DNA-binding subunit.

This entry is found at the C terminus of Replication factor A.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
Pfam