Family

Kinetochore Mis14/Nsl1 (IPR013950)

Short name: Mis14/Nsl1

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry includes Mis14 from S. pombe, Nsl1 from S. cerevisiae and Nsl1 homologues from animals. MIs14 is a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle [PMID: 15369671]. Nsl1 is an essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity [PMID: 14633972].

GO terms

Biological Process

GO:0000070 mitotic sister chromatid segregation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0000776 kinetochore

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER