Domain

Ly49-like, N-terminal (IPR013600)

Short name: Ly49_N

Domain relationships

None.

Description

The sequences making up this entry are annotated as, or are similar to, Ly49 receptors (e.g. P20937). These are type II transmembrane receptors expressed by mouse natural killer (NK) cells. They are classified as being activating (e.g.Ly49D and H) or inhibitory (e.g. Ly49A and G), depending on their effect on NK cell function [PMID: 15607796]. They are members of the C-type lectin receptor superfamily [PMID: 10925254], and in fact in many family members this region is found immediately N-terminal to a lectin C-type domain (IPR001304).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam