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Overview
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Cross-references
Repeat
FG-GAP repeat (IPR013517)
Short name: FG-GAP
Description
This region contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure [PMID: 7929213]. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat [PMID: 7929213]. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding [PMID: 8990162]. A putative Ca2+ binding motif is found in some of the repeats.