Domain

PEP-CTERM protein-sorting domain (IPR013424)

Short name: PEP_exosort_dom

Domain relationships

None.

Description

This entry describes a 25-residue domain including an invariant Pro-Glu-Pro (PEP) motif, a thirteen residue strongly hydrophobic sequence likely to span the membrane, and a five-residue strongly basic motif that often contains four Arg residues. In most cases, this motif is found within nine residues of the C-terminal end of the protein. Proteins containing this motif typically have signal sequences at the N terminus [PMID: 16930487].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
Pfam