Protein CBFA2T1 (IPR013290)

Short name: CBFA2T1

Overlapping homologous superfamilies


Family relationships


Protein CBFA2T1 is a transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes [PMID: 12559562, PMID: 15203199]. It can repress the expression of MMP7 in a ZBTB33-dependent manner [PMID: 23251453] and can repress transactivation mediated by TCF12 [PMID: 16803958].

GO terms

Biological Process

GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

GO:0003714 transcription corepressor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.