Mitochondrial import inner membrane translocase subunit Tim21 (IPR013261)

Short name: Tim21

Overlapping homologous superfamilies

Family relationships



Tim21 is an essential component of the TIM23 complex, which mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Tim21 is required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix [PMID: 15797382, PMID: 15878866, PMID: 15797382].

GO terms

Biological Process

GO:0030150 protein import into mitochondrial matrix

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005744 mitochondrial inner membrane presequence translocase complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.