Family

DASH complex subunit Spc19 (IPR013251)

Short name: DASH_Spc19

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Spc19 is a component of the DASH complex, which is a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore [PMID: 11799062, PMID: 11782438].

GO terms

Biological Process

GO:0008608 attachment of spindle microtubules to kinetochore

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0042729 DASH complex
GO:0005876 spindle microtubule

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER