Domain

M protein trans-acting positive regulator (MGA) HTH domain (IPR013199)

Short name: HTH_Mga_DNA-bd_dom

Overlapping homologous superfamilies

Domain relationships

None.

Description

Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. It appears to contain two DNA-binding domains that are required for direct activation of the Mga virulence regulon in vivo [PMID: 11952907]. This entry represents the Mga DNA binding domain, which also appears to be found in other regulatory proteins.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam