NS5A domain 1a (IPR013192)

Short name: NS5A_1a

Overlapping homologous superfamilies

Domain relationships



The exact function of the Hepatitis C NS5A protein is not known, but it is an active component of the replicase, regulates replication and modulates a range of cellular processes including innate immunity and dysregulated cell growth. The 1a domain binds zinc, which is thought to be crucial for fold maintenance and is essential for replicase function [PMID: 15902263].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.