Vitelline membrane cysteine-rich domain (IPR013135)

Short name: Vitelline_membr_Cys-rich-dom

Overlapping homologous superfamilies


Domain relationships



In Drosophila melanogaster (Fruit fly) the vitelline membrane (VM) is the first layer of the eggshell produced by the follicular epithelium. It is composed of at least four different proteins. VM proteins are similarly organised with a central highly conserved 38-amino acid domain which is flanked by unrelated regions. Since the surrounding regions have diverged significantly, it is possible that the VM domain is of key importance in VM protein structure [PMID: 3143615, PMID: 8293994]. The VM domain contains three highly conserved cysteines.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles