Domain

Gryzun, putative trafficking through Golgi (IPR012880)

Short name: Gryzun

Domain relationships

None.

Description

The proteins featured in this family are all eukaryotic, and many of them are annotated as being Gryzun. Gryzun is distantly related to, but distinct from, the Trs130 subunit of the TRAPP complex but is absent from S. cerevisiae. RNAi of human Gryzun (Q7Z392) blocks Golgi exit. Thus the family is likely to be involved with trafficking of proteins through membranes, perhaps as part of the TRAPP complex [PMID: 19942856].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam