Family

Beta-L-arabinofuranosidase, GH127 (IPR012878)

Short name: Glyco_hydro_127

Overlapping homologous superfamilies

Family relationships

None.

Description

One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterised as an unusual beta-L-arabinofuranosidase enzyme (EC:3.2.1.185). It releases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a number of different plant species. Beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context [PMID: 24385433].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam