Cysteine oxygenase/2-aminoethanethiol dioxygenase (IPR012864)

Short name: PCO/ADO

Overlapping homologous superfamilies

Family relationships



This entry includes cysteine oxidases (PCOs) from plants and 2-aminoethanethiol dioxygenases (ADOs) from animals. PCOs oxidize N-terminal cysteine residues, thus preparing the protein for N-end rule pathway-mediated proteasomal degradation [PMID: 24599061]. ADO is responsible for endogenous cysteamine dioxygenase activity [PMID: 17581819].

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.