D-aminopeptidase, domain B (IPR012856)

Short name: DAP_B_dom

Overlapping homologous superfamilies


Domain relationships



D-aminopeptidase (Q9ZBA9) is a dimeric enzyme with each monomer being composed of three domains. Domain B is organised to form a beta barrel made up of eight antiparallel beta strands. It is connected to domain A, the catalytic domain, by an eight-residue sequence, and also interacts with both domains A and C via non-covalent bonds. Domain B probably functions in maintaining domain C in a good position to interact with the catalytic domain [PMID: 10986464].

This domain is found in peptidases that belong to MEROPS peptidase family S12 (D-Ala-D-Ala carboxypeptidase B family, clan ME).

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004177 aminopeptidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.