ATP-dependent 6-phosphofructokinase, prokaryotic (IPR012828)

Short name: PFKA_ATP_prok

Overlapping homologous superfamilies

Family relationships


6-phosphofructokinase (EC:, a key regulatory enzyme in glycolysis, catalyses the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This entry contains bacterial ATP-dependent 6-phosphofructokinases, which lack a beta-hairpin loop present in IPR012829 family members. IPR012829 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. IPR011183 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC:

GO terms

Biological Process

GO:0006002 fructose 6-phosphate metabolic process
GO:0006096 glycolytic process

Molecular Function

GO:0003872 6-phosphofructokinase activity
GO:0005524 ATP binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.