Fatty acid oxidation complex, alpha subunit, mitochondrial (IPR012803)

Short name: Fa_ox_alpha_mit

Overlapping homologous superfamilies

Family relationships


Members of this family represent the alpha subunit of the mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC: and 3-hydroxyacyl-CoA dehydrogenase (EC: Some characterisation of these proteins has been done in human (P40939), pig (Q29554) and rat (Q64428). The beta subunit has acetyl-CoA C-acyltransferase (EC: activity.

GO terms

Biological Process

GO:0006635 fatty acid beta-oxidation
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004300 enoyl-CoA hydratase activity

Cellular Component

GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0005739 mitochondrion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.