Catechol 1,2-dioxygenase, proteobacteria (IPR012801)

Short name: Cchol_dOase_prob

Overlapping homologous superfamilies

Family relationships



Members of this family known so far are catechol 1,2-dioxygenases of the proteobacteria. They are distinct from catechol 1,2-dioxygenases and chlorocatechol 1,2-dioxygenases of the actinobacteria, which are quite similar to each other and resolved by separate entries. This enzyme catalyses intradiol cleavage in which catechol + O2 becomes cis,cis-muconate. Catechol is an intermediate in the catabolism of many different aromatic compounds, as is the alternative intermediate protocatechuate. In Acinetobacter lwoffii, two isozymes are present with abilities, differing somewhat, to act on catechol analogues 3-methylcatechol, 4-methylcatechol, 4-methoxycatechol, and 4-chlorocatechol.

GO terms

Biological Process

GO:0019614 catechol-containing compound catabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0018576 catechol 1,2-dioxygenase activity
GO:0005506 iron ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.