Magi 5 toxic peptide (IPR012628)

Short name: Toxin_23

Overlapping homologous superfamilies


Family relationships



This family consists of toxic peptides (Magi 5) found in the venom of the Hexathelidae spider. Magi 5 is the first spider toxin with binding affinity to site 4 of a mammalian sodium channel and the toxin has an insecticidal effect on larvae, causing paralysis when injected into the larvae.

This entry also includes some proteins from the omega-atracotoxin type 2 family.

GO terms

Biological Process

GO:0009405 pathogenesis

Molecular Function

GO:0019871 sodium channel inhibitor activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.