Frog antimicrobial peptide, brevinin-2/esculentin type (IPR012521)

Short name: Antimicrobial_frog_2

Overlapping homologous superfamilies


Family relationships



This family consists of the major classes of antimicrobial peptides secreted from the skin of frogs that protect the frogs against invading microbes. They are typically between 10-50 amino acids long and are derived from proteolytic cleavage of larger precursors. Major classes of peptides such esculentin, gaegurin, brevinin-2, rugosin and ranatuerin are included in this family [PMID: 12470734].

GO terms

Biological Process

GO:0006952 defense response

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.